Reference values of pulse wave velocity in healthy children and teenagers.
Identifieur interne : 000108 ( Main/Exploration ); précédent : 000107; suivant : 000109Reference values of pulse wave velocity in healthy children and teenagers.
Auteurs : George S. Reusz [Hongrie] ; Orsolya Cseprekal ; Mohamed Temmar ; Eva Kis ; Abdelghani Bachir Cherif ; Abddelhalim Thaleb ; Andrea Fekete ; Attila J. Szab ; Athanase Benetos ; Paolo SalviSource :
- Hypertension (Dallas, Tex. : 1979) [ 1524-4563 ] ; 2010.
Descripteurs français
- KwdFr :
- Adolescent (MeSH), Algérie (MeSH), Caractères sexuels (MeSH), Enfant (MeSH), Femelle (MeSH), Hongrie (MeSH), Humains (MeSH), Indice de masse corporelle (MeSH), Italie (MeSH), Jeune adulte (MeSH), Mensurations corporelles (MeSH), Mâle (MeSH), Pouls (MeSH), Pression sanguine (physiologie), Rythme cardiaque (physiologie), Taille (MeSH), Valeurs de référence (MeSH).
- MESH :
- Wicri :
English descriptors
- KwdEn :
- Adolescent (MeSH), Algeria (MeSH), Blood Pressure (physiology), Body Height (MeSH), Body Mass Index (MeSH), Body Size (MeSH), Child (MeSH), Female (MeSH), Heart Rate (physiology), Humans (MeSH), Hungary (MeSH), Italy (MeSH), Male (MeSH), Pulse (MeSH), Reference Values (MeSH), Sex Characteristics (MeSH), Young Adult (MeSH).
- MESH :
- geographic : Algeria, Hungary, Italy.
- physiology : Blood Pressure, Heart Rate.
- Adolescent, Body Height, Body Mass Index, Body Size, Child, Female, Humans, Male, Pulse, Reference Values, Sex Characteristics, Young Adult.
Abstract
Carotid-femoral pulse wave velocity is an established method for characterizing aortic stiffness, an individual predictor of cardiovascular mortality in adults. Normal pulse wave velocity values for the pediatric population derived from a large data collection have yet to be available. The aim of this study was to create a reference database and to characterize the factors determining pulse wave velocity in children and teenagers. Carotid-femoral pulse wave velocity was measured by applanation tonometry. Reference tables from pulse wave velocities obtained in 1008 healthy subjects (aged between 6 and 20 years; 495 males) were generated using a maximum-likelihood curve-fitting technique for calculating SD scores in accordance with the skewed distribution of the raw data. Effects of sex, age, height, weight, blood pressure, and heart rate on pulse wave velocity were assessed. Sex-specific reference tables and curves for age and height are presented. Pulse wave velocity correlated positively (P<0.001) with age, height, weight, and blood pressure while correlating negatively with heart rate. After multiple regression analysis, age, height, and blood pressure remained major predictors of pulse wave velocity. This study, involving >1000 children, is the first to provide reference values for pulse wave velocity in children and teenagers, thereby constituting a suitable tool for longitudinal clinical studies assessing subgroups of children who are at long-term risk of cardiovascular disease.
DOI: 10.1161/HYPERTENSIONAHA.110.152686
PubMed: 20566959
Affiliations:
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Le document en format XML
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Reusz</name><affiliation wicri:level="3"><nlm:affiliation>First Department of Pediatrics, Semmelweis University, Budapest, Budapest, Hungary. reusz@gyer1.sote.hu</nlm:affiliation><country xml:lang="fr">Hongrie</country><wicri:regionArea>First Department of Pediatrics, Semmelweis University, Budapest, Budapest</wicri:regionArea><placeName><settlement type="city">Budapest</settlement><region nuts="2">Hongrie centrale</region></placeName></affiliation></author><author><name sortKey="Cseprekal, Orsolya" sort="Cseprekal, Orsolya" uniqKey="Cseprekal O" first="Orsolya" last="Cseprekal">Orsolya Cseprekal</name></author><author><name sortKey="Temmar, Mohamed" sort="Temmar, Mohamed" uniqKey="Temmar M" first="Mohamed" last="Temmar">Mohamed Temmar</name></author><author><name sortKey="Kis, Eva" sort="Kis, Eva" uniqKey="Kis E" first="Eva" last="Kis">Eva Kis</name></author><author><name sortKey="Cherif, Abdelghani Bachir" sort="Cherif, Abdelghani Bachir" uniqKey="Cherif A" first="Abdelghani Bachir" last="Cherif">Abdelghani Bachir Cherif</name></author><author><name sortKey="Thaleb, Abddelhalim" sort="Thaleb, Abddelhalim" uniqKey="Thaleb A" first="Abddelhalim" last="Thaleb">Abddelhalim Thaleb</name></author><author><name sortKey="Fekete, Andrea" sort="Fekete, Andrea" uniqKey="Fekete A" first="Andrea" last="Fekete">Andrea Fekete</name></author><author><name sortKey="Szab, Attila J" sort="Szab, Attila J" uniqKey="Szab A" first="Attila J" last="Szab">Attila J. Szab</name></author><author><name sortKey="Benetos, Athanase" sort="Benetos, Athanase" uniqKey="Benetos A" first="Athanase" last="Benetos">Athanase Benetos</name></author><author><name sortKey="Salvi, Paolo" sort="Salvi, Paolo" uniqKey="Salvi P" first="Paolo" last="Salvi">Paolo Salvi</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2010">2010</date><idno type="RBID">pubmed:20566959</idno><idno type="pmid">20566959</idno><idno type="doi">10.1161/HYPERTENSIONAHA.110.152686</idno><idno type="wicri:Area/PubMed/Corpus">000709</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000709</idno><idno type="wicri:Area/PubMed/Curation">000705</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000705</idno><idno type="wicri:Area/PubMed/Checkpoint">000702</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000702</idno><idno type="wicri:Area/Main/Merge">000108</idno><idno type="wicri:Area/Main/Curation">000108</idno><idno type="wicri:Area/Main/Exploration">000108</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Reference values of pulse wave velocity in healthy children and teenagers.</title><author><name sortKey="Reusz, George S" sort="Reusz, George S" uniqKey="Reusz G" first="George S" last="Reusz">George S. Reusz</name><affiliation wicri:level="3"><nlm:affiliation>First Department of Pediatrics, Semmelweis University, Budapest, Budapest, Hungary. reusz@gyer1.sote.hu</nlm:affiliation><country xml:lang="fr">Hongrie</country><wicri:regionArea>First Department of Pediatrics, Semmelweis University, Budapest, Budapest</wicri:regionArea><placeName><settlement type="city">Budapest</settlement><region nuts="2">Hongrie centrale</region></placeName></affiliation></author><author><name sortKey="Cseprekal, Orsolya" sort="Cseprekal, Orsolya" uniqKey="Cseprekal O" first="Orsolya" last="Cseprekal">Orsolya Cseprekal</name></author><author><name sortKey="Temmar, Mohamed" sort="Temmar, Mohamed" uniqKey="Temmar M" first="Mohamed" last="Temmar">Mohamed Temmar</name></author><author><name sortKey="Kis, Eva" sort="Kis, Eva" uniqKey="Kis E" first="Eva" last="Kis">Eva Kis</name></author><author><name sortKey="Cherif, Abdelghani Bachir" sort="Cherif, Abdelghani Bachir" uniqKey="Cherif A" first="Abdelghani Bachir" last="Cherif">Abdelghani Bachir Cherif</name></author><author><name sortKey="Thaleb, Abddelhalim" sort="Thaleb, Abddelhalim" uniqKey="Thaleb A" first="Abddelhalim" last="Thaleb">Abddelhalim Thaleb</name></author><author><name sortKey="Fekete, Andrea" sort="Fekete, Andrea" uniqKey="Fekete A" first="Andrea" last="Fekete">Andrea Fekete</name></author><author><name sortKey="Szab, Attila J" sort="Szab, Attila J" uniqKey="Szab A" first="Attila J" last="Szab">Attila J. Szab</name></author><author><name sortKey="Benetos, Athanase" sort="Benetos, Athanase" uniqKey="Benetos A" first="Athanase" last="Benetos">Athanase Benetos</name></author><author><name sortKey="Salvi, Paolo" sort="Salvi, Paolo" uniqKey="Salvi P" first="Paolo" last="Salvi">Paolo Salvi</name></author></analytic><series><title level="j">Hypertension (Dallas, Tex. : 1979)</title><idno type="eISSN">1524-4563</idno><imprint><date when="2010" type="published">2010</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adolescent (MeSH)</term><term>Algeria (MeSH)</term><term>Blood Pressure (physiology)</term><term>Body Height (MeSH)</term><term>Body Mass Index (MeSH)</term><term>Body Size (MeSH)</term><term>Child (MeSH)</term><term>Female (MeSH)</term><term>Heart Rate (physiology)</term><term>Humans (MeSH)</term><term>Hungary (MeSH)</term><term>Italy (MeSH)</term><term>Male (MeSH)</term><term>Pulse (MeSH)</term><term>Reference Values (MeSH)</term><term>Sex Characteristics (MeSH)</term><term>Young Adult (MeSH)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adolescent (MeSH)</term><term>Algérie (MeSH)</term><term>Caractères sexuels (MeSH)</term><term>Enfant (MeSH)</term><term>Femelle (MeSH)</term><term>Hongrie (MeSH)</term><term>Humains (MeSH)</term><term>Indice de masse corporelle (MeSH)</term><term>Italie (MeSH)</term><term>Jeune adulte (MeSH)</term><term>Mensurations corporelles (MeSH)</term><term>Mâle (MeSH)</term><term>Pouls (MeSH)</term><term>Pression sanguine (physiologie)</term><term>Rythme cardiaque (physiologie)</term><term>Taille (MeSH)</term><term>Valeurs de référence (MeSH)</term></keywords><keywords scheme="MESH" type="geographic" xml:lang="en"><term>Algeria</term><term>Hungary</term><term>Italy</term></keywords><keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Pression sanguine</term><term>Rythme cardiaque</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Blood Pressure</term><term>Heart Rate</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adolescent</term><term>Body Height</term><term>Body Mass Index</term><term>Body Size</term><term>Child</term><term>Female</term><term>Humans</term><term>Male</term><term>Pulse</term><term>Reference Values</term><term>Sex Characteristics</term><term>Young Adult</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adolescent</term><term>Algérie</term><term>Caractères sexuels</term><term>Enfant</term><term>Femelle</term><term>Hongrie</term><term>Humains</term><term>Indice de masse corporelle</term><term>Italie</term><term>Jeune adulte</term><term>Mensurations corporelles</term><term>Mâle</term><term>Pouls</term><term>Taille</term><term>Valeurs de référence</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Algérie</term><term>Hongrie</term><term>Italie</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Carotid-femoral pulse wave velocity is an established method for characterizing aortic stiffness, an individual predictor of cardiovascular mortality in adults. Normal pulse wave velocity values for the pediatric population derived from a large data collection have yet to be available. The aim of this study was to create a reference database and to characterize the factors determining pulse wave velocity in children and teenagers. Carotid-femoral pulse wave velocity was measured by applanation tonometry. Reference tables from pulse wave velocities obtained in 1008 healthy subjects (aged between 6 and 20 years; 495 males) were generated using a maximum-likelihood curve-fitting technique for calculating SD scores in accordance with the skewed distribution of the raw data. Effects of sex, age, height, weight, blood pressure, and heart rate on pulse wave velocity were assessed. Sex-specific reference tables and curves for age and height are presented. Pulse wave velocity correlated positively (P<0.001) with age, height, weight, and blood pressure while correlating negatively with heart rate. After multiple regression analysis, age, height, and blood pressure remained major predictors of pulse wave velocity. This study, involving >1000 children, is the first to provide reference values for pulse wave velocity in children and teenagers, thereby constituting a suitable tool for longitudinal clinical studies assessing subgroups of children who are at long-term risk of cardiovascular disease.</div></front></TEI><affiliations><list><country><li>Hongrie</li></country><region><li>Hongrie centrale</li></region><settlement><li>Budapest</li></settlement></list><tree><noCountry><name sortKey="Benetos, Athanase" sort="Benetos, Athanase" uniqKey="Benetos A" first="Athanase" last="Benetos">Athanase Benetos</name><name sortKey="Cherif, Abdelghani Bachir" sort="Cherif, Abdelghani Bachir" uniqKey="Cherif A" first="Abdelghani Bachir" last="Cherif">Abdelghani Bachir Cherif</name><name sortKey="Cseprekal, Orsolya" sort="Cseprekal, Orsolya" uniqKey="Cseprekal O" first="Orsolya" last="Cseprekal">Orsolya Cseprekal</name><name sortKey="Fekete, Andrea" sort="Fekete, Andrea" uniqKey="Fekete A" first="Andrea" last="Fekete">Andrea Fekete</name><name sortKey="Kis, Eva" sort="Kis, Eva" uniqKey="Kis E" first="Eva" last="Kis">Eva Kis</name><name sortKey="Salvi, Paolo" sort="Salvi, Paolo" uniqKey="Salvi P" first="Paolo" last="Salvi">Paolo Salvi</name><name sortKey="Szab, Attila J" sort="Szab, Attila J" uniqKey="Szab A" first="Attila J" last="Szab">Attila J. Szab</name><name sortKey="Temmar, Mohamed" sort="Temmar, Mohamed" uniqKey="Temmar M" first="Mohamed" last="Temmar">Mohamed Temmar</name><name sortKey="Thaleb, Abddelhalim" sort="Thaleb, Abddelhalim" uniqKey="Thaleb A" first="Abddelhalim" last="Thaleb">Abddelhalim Thaleb</name></noCountry><country name="Hongrie"><region name="Hongrie centrale"><name sortKey="Reusz, George S" sort="Reusz, George S" uniqKey="Reusz G" first="George S" last="Reusz">George S. Reusz</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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